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Idelalisib (CAL-101) chemical structure

Idelalisib (CAL-101)

Regular price $110.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
PI3K/Akt/mTOR
Cas number
870281-82-6
Formula
C22H18FN7O
Small target
PI3K
Smiles
CCC(C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
Storage conditions
2 years -80 in solvent
Synonyms
GS-1101
Scientific background
Idelalisib (CAL-101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.
Technical documents

Documents

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