Buparlisib (BKM120)

Name: Buparlisib (BKM120)
Brand: Selleckchem
Price: 128.0 USD
Availability: InStock

Vendor: Selleckchem

Type: PI3K/Akt/mTOR

SKU: S2247-5mg

$128.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

PI3K/Akt/mTOR

Cas number

944396-07-0

Formula

C18H21F3N6O2

Small target

PI3K

Smiles

C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4

Storage conditions

2 years -80 in solvent

Synonyms

NVP-BKM120

Background

Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.

Buparlisib (BKM120)

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Product Overview

Background

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