Silmitasertib (CX-4945) chemical structure

Silmitasertib (CX-4945)

Vendor: Selleckchem

Type: Cell Cycle

SKU: S2248-2mg

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For research use only — not intended for clinical or diagnostic purposes.
Silmitasertib (CX-4945) chemical structure

Silmitasertib (CX-4945)

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
1009820-21-6
Formula
C19H12ClN3O2
Small target
Casein Kinase
Smiles
C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)O)C4=C2C=CN=C4
Storage conditions
2 years -80 in solvent
Scientific background
Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2.
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