Gambogic Acid chemical structure

Gambogic Acid

Vendor: Selleckchem

Type: Apoptosis

SKU: S2448-5mg

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Gambogic Acid chemical structure

Gambogic Acid

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
2752-65-0
Formula
C38H44O8
Small target
Bcl-2
Smiles
CC(=CCCC1(C=CC2=C(C3=C(C(=C2O1)CC=C(C)C)OC45C6CC(C=C4C3=O)C(=O)C5(OC6(C)C)CC=C(C)C(=O)O)O)C)C
Storage conditions
2 years -80 in solvent
Synonyms
Guttatic Acid, Guttic Acid, Beta-Guttiferrin
Scientific background
Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
Technical documents

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