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PP121 chemical structure

PP121

Regular price $110.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
PI3K/Akt/mTOR
Cas number
1092788-83-4
Formula
C17H17N7
Small target
DNA-PK
Smiles
C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CN=C5C(=C4)C=CN5)N
Storage conditions
2 years -80 in solvent
Scientific background
PP-121 is a multi-targeted inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM and 18 nM, also inhibits DNA-PK with IC50 of 60 nM.
Technical documents

Documents

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