Rebastinib (DCC-2036) chemical structure

Rebastinib (DCC-2036)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2634-10mg

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Rebastinib (DCC-2036) chemical structure

Rebastinib (DCC-2036)

$240.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1020172-07-9
Formula
C30H28FN7O3
Small target
Bcr-Abl
Smiles
CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
Storage conditions
2 years -80 in solvent
Scientific background
Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1.
Technical documents

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