Omipalisib (GSK2126458)

Name: Omipalisib (GSK2126458)
Brand: Selleckchem
Price: 128.0 USD
Availability: InStock

Vendor: Selleckchem

Type: PI3K/Akt/mTOR

SKU: S2658-2mg

$128.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

PI3K/Akt/mTOR

Cas number

1086062-66-9

Formula

C25H17F2N5O3S

Small target

mTOR

Smiles

COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F

Storage conditions

2 years -80 in solvent

Synonyms

GSK458

Background

Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib induces autophagy. Phase 1.

Omipalisib (GSK2126458)

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Product Overview

Background

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