Ibrutinib chemical structure

Ibrutinib

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2680-5mg

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Ibrutinib chemical structure

Ibrutinib

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
936563-96-1
Formula
C25H24N6O2
Small target
BTK
Smiles
C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Storage conditions
2 years -80 in solvent
Synonyms
PCI-32765
Scientific background
Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.
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