AMG-458 chemical structure

AMG-458

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2747-5mg

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For research use only — not intended for clinical or diagnostic purposes.
AMG-458 chemical structure

AMG-458

$203.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
913376-83-7
Formula
C30H29N5O5
Small target
c-Met
Smiles
CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC
Storage conditions
2 years -80 in solvent
Scientific background
AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
Technical documents

Documents

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