Dinaciclib chemical structure

Dinaciclib

Vendor: Selleckchem

Type: Cell Cycle

SKU: S2768-5mg

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Dinaciclib chemical structure

Dinaciclib

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
779353-01-4
Formula
C21H28N6O2
Small target
CDK
Smiles
CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCCC4CCO
Storage conditions
2 years -80 in solvent
Synonyms
SCH727965, PS-095760
Scientific background
Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.
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