Vistusertib (AZD2014)

Name: Vistusertib (AZD2014)
Brand: Selleckchem
Price: 128.0 USD
Availability: InStock

Vendor: Selleckchem

Type: PI3K/Akt/mTOR

SKU: S2783-5mg

$128.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

PI3K/Akt/mTOR

Cas number

1009298-59-2

Formula

C25H30N6O3

Small target

mTOR

Smiles

CC1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=CC=C4)C(=O)NC)N5CCOCC5C

Storage conditions

2 years -80 in solvent

Background

Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (α/β/γ/δ). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 μM. AZD2014 induces proliferation suppression, apoptosis, cell cycle arrest, and autophagy in HCC cells with antitumor activity.

Vistusertib (AZD2014)

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Product Overview

Background

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