Lonafarnib (SCH66336) chemical structure

Lonafarnib (SCH66336)

Vendor: Selleckchem

Type: Metabolism

SKU: S2797-5mg

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Lonafarnib (SCH66336) chemical structure

Lonafarnib (SCH66336)

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
193275-84-2
Formula
C27H31Br2ClN4O2
Small target
Transferase
Smiles
C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
Storage conditions
2 years -80 in solvent
Scientific background
Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.
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