Fexagratinib (AZD4547) chemical structure

Fexagratinib (AZD4547)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2801-5mg

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Fexagratinib (AZD4547) chemical structure

Fexagratinib (AZD4547)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1035270-39-3
Formula
C26H33N5O3
Small target
FGFR
Smiles
CC1CN(CC(N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC
Storage conditions
2 years -80 in solvent
Synonyms
ABSK 091
Scientific background
Fexagratinib (AZD4547,ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.
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