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WHI-P154 chemical structure

WHI-P154

Regular price $83.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
211555-04-3
Formula
C16H14BrN3O3
Small target
EGFR
Smiles
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC
Storage conditions
2 years -80 in solvent
Scientific background
WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
Technical documents

Documents

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