PF-562271 chemical structure

PF-562271

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S2890-5mg

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For research use only — not intended for clinical or diagnostic purposes.
PF-562271 chemical structure

PF-562271

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
717907-75-0
Formula
C21H20F3N7O3S
Small target
FAK
Smiles
CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
Storage conditions
2 years -80 in solvent
Synonyms
PF-00562271
Scientific background
PF-562271 (PF-00562271) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
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