VU 0361737 chemical structure

VU 0361737

Vendor: Selleckchem

Type: Neuronal Signaling

SKU: S2892-10mg

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VU 0361737 chemical structure

VU 0361737

$68.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Neuronal Signaling
Cas number
1161205-04-4
Formula
C13H11ClN2O2
Small target
GluR
Smiles
COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
Storage conditions
2 years -80 in solvent
Scientific background
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.
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