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Salubrinal chemical structure

Salubrinal

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
405060-95-9
Formula
C21H17Cl3N4OS
Small target
PERK
Smiles
C1=CC=C(C=C1)C=CC(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3
Storage conditions
2 years -80 in solvent
Scientific background
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM in a cell-free assay.
Technical documents

Documents

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