Apoptosis Activator 2 chemical structure

Apoptosis Activator 2

Vendor: Selleckchem

Type: Apoptosis

SKU: S2927-10mg

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$110.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Apoptosis Activator 2 chemical structure

Apoptosis Activator 2

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
79183-19-0
Formula
C15H9Cl2NO2
Small target
Caspase
Smiles
C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl
Storage conditions
2 years -80 in solvent
Scientific background
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells.
Technical documents

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