Dooku1 chemical structure

Dooku1

Vendor: Selleckchem

Type: Transmembrane Transporters

SKU: S2953-5mg

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$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Dooku1 chemical structure

Dooku1

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Transmembrane Transporters
Cas number
2253744-54-4
Formula
C13H9Cl2N3OS
Small target
Mechanosensitive Channel
Smiles
ClC1=C(CSC2=NN=C(O2)C3=CC=C[NH]3)C(=CC=C1)Cl
Storage conditions
3 years -20°C powder
Scientific background
Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.
Technical documents

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