Amitriptyline HCl chemical structure

Amitriptyline HCl

Vendor: Selleckchem

Type: Neuronal Signaling

SKU: S3183-50mg

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Amitriptyline HCl chemical structure

Amitriptyline HCl

$73.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Neuronal Signaling
Cas number
549-18-8
Formula
C20H23N.HCl
Small target
Histamine Receptor
Smiles
CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Storage conditions
2 years -80 in solvent
Scientific background
Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline HCl also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. Amitriptyline is a tricyclic antidepressant (TCA).
Technical documents

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