Harmine hydrochloride chemical structure

Harmine hydrochloride

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S3817-1g

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Harmine hydrochloride chemical structure

Harmine hydrochloride

$1,478.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
343-27-1
Formula
C13H12N2O.HCl
Small target
DYRK
Smiles
CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC.Cl
Storage conditions
2 years -80 in solvent
Synonyms
Telepathine hydrochloride
Scientific background
Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.
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