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Teriflunomide chemical structure

Teriflunomide

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
163451-81-8
Formula
C12H9F3N2O2
Small target
Dehydrogenase
Smiles
CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
Storage conditions
2 years -80 in solvent
Synonyms
A77 1726, HMR-1726
Scientific background
Teriflunomide (A77 1726, HMR-1726) is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.
Technical documents

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