Apatinib chemical structure

Apatinib

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S5248-5mg

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Apatinib chemical structure

Apatinib

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
811803-05-1
Formula
C24H23N5O
Small target
VEGFR
Smiles
O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3
Storage conditions
3 years -20°C powder
Synonyms
Rivoceranib, YN968D1
Scientific background
Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.
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