PMX-53 chemical structure

PMX-53

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: S6239-5mg

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For research use only — not intended for clinical or diagnostic purposes.
PMX-53 chemical structure

PMX-53

$185.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
219639-75-5
Formula
C47H65N11O7
Small target
Immunology & Inflammation related
Smiles
CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5CCCCC5)NC(=O)C6CCCN6C2=O
Storage conditions
3 years -20°C powder
Scientific background
PMX-53 is a potent CD88 (C5aR) antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).
Technical documents

Documents

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