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(R)-GNE-140 chemical structure

(R)-GNE-140

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
2003234-63-5
Formula
C25H23ClN2O3S2
Small target
Dehydrogenase
Smiles
C1COCCN1C2=CC=C(C=C2)C3(CC(=C(C(=O)N3)SC4=CC=CC=C4Cl)O)C5=CSC=C5
Storage conditions
3 years -20°C powder
Scientific background
(R)-GNE-140 is an inhibitory agent for LDHA, LDHB, and LDHC, with IC50 values ​​of 3 nM and 5 nM for LDHA and LDHB, respectively. (R)-GNE-140 is 18 times more potent than its S isomer.
Technical documents

Documents

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