Epertinib hydrochloride chemical structure

Epertinib hydrochloride

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S6897-5mg

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Epertinib hydrochloride chemical structure

Epertinib hydrochloride

$278.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
2071195-74-7
Formula
C30H28Cl2FN5O3
Small target
EGFR
Smiles
Cl.CC#CC(=N\OCC1COCCN1)/C2=CC3=C(C=C2)N=CN=C3NC4=CC=C(OCC5=CC(=CC=C5)F)C(=C4)Cl
Storage conditions
3 years -20°C powder
Synonyms
Epertinib HCl, S-222611 hydrochloride, S-222611 HCl
Scientific background
Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4 with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity.
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