MT-802 chemical structure

MT-802

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S6966-5mg

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For research use only — not intended for clinical or diagnostic purposes.
MT-802 chemical structure

MT-802

$449.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
2231744-29-7
Formula
C41H41N9O8
Small target
BTK
Smiles
NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCN(CCOCCOCC(=O)NC6=CC7=C(C=C6)C(=O)N(C8CCC(=O)NC8=O)C7=O)CC5
Storage conditions
3 years -20°C powder
Scientific background
MT-802 is a potent PROTAC that induces Bruton's tyrosine kinase (BTK) knockdown. MT-802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT-802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL).
Technical documents

Documents

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