Binimetinib (MEK162) chemical structure

Binimetinib (MEK162)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S7007-10mg

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Binimetinib (MEK162) chemical structure

Binimetinib (MEK162)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
606143-89-9
Formula
C17H15BrF2N4O3
Small target
MEK
Smiles
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO
Storage conditions
2 years -80 in solvent
Synonyms
ARRY-162,ARRY-438162
Scientific background
Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3.
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