GDC-0152 chemical structure

GDC-0152

Vendor: Selleckchem

Type: Apoptosis

SKU: S7010-10mg

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For research use only — not intended for clinical or diagnostic purposes.
GDC-0152 chemical structure

GDC-0152

$203.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
873652-48-3
Formula
C25H34N6O3S
Small target
IAP
Smiles
CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC
Storage conditions
2 years -80 in solvent
Scientific background
GDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
Technical documents

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