LY2874455 chemical structure

LY2874455

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S7057-5mg

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LY2874455 chemical structure

LY2874455

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1254473-64-7
Formula
C21H19Cl2N5O2
Small target
FGFR
Smiles
CC(C1=C(C=NC=C1Cl)Cl)OC2=CC3=C(C=C2)NN=C3C=CC4=CN(N=C4)CCO
Storage conditions
2 years -80 in solvent
Scientific background
LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.
Technical documents

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