SC144 chemical structure

SC144

Vendor: Selleckchem

Type: Neuronal Signaling

SKU: S7124-5mg

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SC144 chemical structure

SC144

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Neuronal Signaling
Cas number
895158-95-9
Formula
C16H11FN6O
Small target
P-gp
Smiles
C1=CN2C3=C(C=C(C=C3)F)N=C(C2=C1)NNC(=O)C4=NC=CN=C4
Storage conditions
2 years -80 in solvent
Scientific background
SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.
Technical documents

Documents

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