Onvansertib (NMS-P937) chemical structure

Onvansertib (NMS-P937)

Vendor: Selleckchem

Type: Cell Cycle

SKU: S7255-10mg

Explore specifications & documents
$209.00 USD
Shipping calculated at checkout.

Documents

MSDS

Available in stock (500)

Request a quotation
  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.
Onvansertib (NMS-P937) chemical structure

Onvansertib (NMS-P937)

$209.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
1034616-18-6
Formula
C24H27F3N8O3
Small target
PLK
Smiles
CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO
Storage conditions
2 years -80 in solvent
Synonyms
PCM-075, NMS1286937
Scientific background
Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.
Technical documents

Documents

MSDS

A PARTNER IN YOUR RESEARCH

More time for discovery. Less time sourcing.

Bring your laboratory requirements together with scientific advice, global sourcing and dedicated procurement support.

Explore our services

Starting a new laboratory?

Plan your laboratory with our New-Lab programme.

Discover New-Lab