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TEPP-46 (ML265) chemical structure

TEPP-46 (ML265)

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
1221186-53-3
Formula
C17H16N4O2S2
Small target
PKM
Smiles
CN1C2=C(C3=C1C(=O)N(N=C3)CC4=CC(=CC=C4)N)SC(=C2)S(=O)C
Storage conditions
2 years -80 in solvent
Synonyms
CID-44246499, NCGC00186528
Scientific background
TEPP-46 (ML265, CID-44246499, NCGC00186528) is a potent activator of PKM2 in both biochemical (AC50 = 92 nM) and cell-based assays with high selectivity over PKM1, PKR and PKL.
Technical documents

Documents

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