LDC1267 chemical structure

LDC1267

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S7638-5mg

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For research use only — not intended for clinical or diagnostic purposes.
LDC1267 chemical structure

LDC1267

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1361030-48-9
Formula
C30H26F2N4O5
Small target
Tyro3
Smiles
CCOC1=CN(N=C1C(=O)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)F)C5=C(C=C(C=C5)F)C
Storage conditions
2 years -80 in solvent
Scientific background
LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.
Technical documents

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