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Zoligratinib (Debio-1347) chemical structure

Zoligratinib (Debio-1347)

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1265229-25-1
Formula
C20H16N6O
Small target
FGFR
Smiles
CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
Storage conditions
2 years -80 in solvent
Synonyms
CH5183284, FF284
Scientific background
Zoligratinib (Debio-1347, CH5183284, FF284) is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1.
Technical documents

Documents

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