Picropodophyllin (PPP) chemical structure

Picropodophyllin (PPP)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S7668-5mg

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Picropodophyllin (PPP) chemical structure

Picropodophyllin (PPP)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
477-47-4
Formula
C22H22O8
Small target
IGF-1R
Smiles
COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
Storage conditions
2 years -80 in solvent
Synonyms
AXL1717
Scientific background
Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R). Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.
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