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Akti-1/2 chemical structure

Akti-1/2

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
PI3K/Akt/mTOR
Cas number
612847-09-3
Formula
C34H29N7O
Small target
Akt
Smiles
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(N=C6C=C7C(=NC=N7)C=C6N5)C8=CC=CC=C8
Storage conditions
2 years -80 in solvent
Synonyms
Akt Inhibitor VIII
Scientific background
Akti-1/2 (Akt Inhibitor VIII) is a highly selective Akt1/Akt2 inhibitor with IC50 of 58 nM/210 nM, respectively, about 36-fold selectivity for Akt1 over Akt3. Akti-1/2 induces apoptosis.
Technical documents

Documents

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