Purvalanol A chemical structure

Purvalanol A

Vendor: Selleckchem

Type: Cell Cycle

SKU: S7793-5mg

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For research use only — not intended for clinical or diagnostic purposes.
Purvalanol A chemical structure

Purvalanol A

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
212844-53-6
Formula
C19H25ClN6O
Small target
CDK
Smiles
CC(C)C(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC=C3)Cl
Storage conditions
2 years -80 in solvent
Scientific background
Purvalanol A is a potent, and cell-permeable CDK inhibitor with IC50 of 4 nM, 70 nM, 35 nM, and 850 nM for cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, and cdk4-cyclin D1, respectively. Purvalanol A induces endoplasmic reticulum stress-mediated apoptosis and autophagy.
Technical documents

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