Nazartinib (EGF816) chemical structure

Nazartinib (EGF816)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S7824-5mg

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Nazartinib (EGF816) chemical structure

Nazartinib (EGF816)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1508250-71-2
Formula
C26H31ClN6O2
Small target
EGFR
Smiles
CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl
Storage conditions
2 years -80 in solvent
Synonyms
NVS-816
Scientific background
Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Technical documents

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