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Ac-DEVD-CHO chemical structure

Ac-DEVD-CHO

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
169332-60-9
Formula
C20H30N4O11
Small target
Caspase
Smiles
CC(C)C(C(=O)NC(CC(=O)O)C=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C
Storage conditions
2 years -80 in solvent
Synonyms
Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO
Scientific background
Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2.
Technical documents

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