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Epacadostat (INCB024360) chemical structure

Epacadostat (INCB024360)

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
1204669-58-8
Formula
C11H13BrFN7O4S
Small target
IDO/TDO
Smiles
C1=CC(=C(C=C1N=C(C2=NON=C2NCCNS(=O)(=O)N)NO)Br)F
Storage conditions
2 years -80 in solvent
Scientific background
Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).
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