Nutlin-3a chemical structure

Nutlin-3a

Vendor: Selleckchem

Type: Apoptosis

SKU: S8059-5mg

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For research use only — not intended for clinical or diagnostic purposes.
Nutlin-3a chemical structure

Nutlin-3a

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
675576-98-4
Formula
C30H30Cl2N4O4
Small target
MDM2/MDMX
Smiles
CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Storage conditions
2 years -80 in solvent
Synonyms
(-)-Nutlin-3
Scientific background
Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner.
Technical documents

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