GNF-7 chemical structure

GNF-7

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S8140-5mg

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GNF-7 chemical structure

GNF-7

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
839706-07-9
Formula
C28H24F3N7O2
Small target
Bcr-Abl
Smiles
CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CN=C(C=C5)C
Storage conditions
2 years -80 in solvent
Scientific background
GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.
Technical documents

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