PD0166285 chemical structure

PD0166285

Vendor: Selleckchem

Type: Cell Cycle

SKU: S8148-5mg

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For research use only — not intended for clinical or diagnostic purposes.
PD0166285 chemical structure

PD0166285

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
185039-89-8
Formula
C26H27Cl2N5O2
Small target
Wee1
Smiles
CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
Storage conditions
2 years -80 in solvent
Scientific background
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1). PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.
Technical documents

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