BMS-935177 chemical structure

BMS-935177

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S8348-2mg

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BMS-935177 chemical structure

BMS-935177

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1231889-53-4
Formula
C31H26N4O3
Small target
BTK
Smiles
CC1=C(C=CC=C1N2C=NC3=CC=CC=C3C2=O)C4=C5C6=C(C=C(C=C6)C(C)(C)O)NC5=C(C=C4)C(=O)N
Storage conditions
2 years -80 in solvent
Scientific background
BMS-935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2.8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective.
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