Tucatinib chemical structure

Tucatinib

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S8362-5mg

Explore specifications & documents
$110.00 USD
Shipping calculated at checkout.

Documents

MSDS

Available in stock (500)

Request a quotation
  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.
Tucatinib chemical structure

Tucatinib

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
937263-43-9
Formula
C26H24N8O2
Small target
HER2
Smiles
CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
Storage conditions
2 years -80 in solvent
Synonyms
Irbinitinib, ONT-380, ARRY-380
Scientific background
Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.
Technical documents

Documents

MSDS

A PARTNER IN YOUR RESEARCH

More time for discovery. Less time sourcing.

Bring your laboratory requirements together with scientific advice, global sourcing and dedicated procurement support.

Explore our services

Starting a new laboratory?

Plan your laboratory with our New-Lab programme.

Discover New-Lab