ND646 chemical structure

ND646

Vendor: Selleckchem

Type: Metabolism

SKU: S8377-5mg

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For research use only — not intended for clinical or diagnostic purposes.
ND646 chemical structure

ND646

$224.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
1434639-57-2
Formula
C28H32N4O7S
Small target
Acetyl-CoA carboxylase
Smiles
COC1=CC=CC=C1C(CN2C(=O)N(C(=O)C3=C2SC(=C3C)C4=NC=CO4)C(C)(C)C(N)=O)OC5CCOCC5
Storage conditions
3 years -20°C powder
Scientific background
ND-646 is an allosteric inhibitor of the ACC (Acetyl-coA carboxylase) enzymes that prevents ACC subunit dimerization to suppress fatty acid synthesis with IC50 of 3.5 nM and 4.1 nM for hACC1 and hACC2, respectively.
Technical documents

Documents

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