Fenebrutinib (GDC-0853) chemical structure

Fenebrutinib (GDC-0853)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S8421-2mg

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Fenebrutinib (GDC-0853) chemical structure

Fenebrutinib (GDC-0853)

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1434048-34-6
Formula
C37H44N8O4
Small target
BTK
Smiles
CC1CN(CCN1C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=NC=C4)N5CCN6C7=C(CC(C7)(C)C)C=C6C5=O)CO)C8COC8
Storage conditions
3 years -20°C powder
Scientific background
Fenebrutinib (GDC-0853) is a potent, selective, and non-covalent bruton's tyrosine kinase (BTK) inhibitor with an Ki value of 0.91 nM for Btk with >100-fold selectivity over 3 off-targets (Bmx :153-fold, Fgr: 168-fold, Src:131-fold).
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