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Asciminib (ABL001) chemical structure

Asciminib (ABL001)

Regular price $110.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1492952-76-7
Formula
C20H18ClF2N5O3
Small target
Bcr-Abl
Smiles
C1CN(CC1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=CC=NN4
Storage conditions
2 years -80 in solvent
Scientific background
Asciminib (ABL001) is a potent and selective allosteric ABL1 inhibitor with dissociation constant (Kd) of 0.5-0.8 nM and selectivity to the myristoyl pocket of ABL1.
Technical documents

Documents

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