Selitrectinib (LOXO-195)

Name: Selitrectinib (LOXO-195)
Brand: Selleckchem
Price: 118.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S8636-5mg

$118.00 USD

Shipping calculated at checkout.

Documents

MSDS

Available in stock (500)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

2097002-61-2

Formula

C20H21FN6O

Small target

Trk receptor

Smiles

CC1CCC2=C(C=C(C=N2)F)C3CCCN3C4=NC5=C(C=NN5C=C4)C(=O)N1

Storage conditions

3 years -20°C powder

Synonyms

BAY 2731954

Background

Selitrectinib (LOXO-195, BAY 2731954) is an orally available, highly potent, and selective TRK kinase inhibitor with low nanomolar inhibitory activity against TRKA G595R, TRKC G623R, and TRKA G667C, IC50s ranging from 2.0 to 9.8 nmol/L. It is more than 1,000-fold selective for 98% of non-TRK kinases tested.

Selitrectinib (LOXO-195)

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info